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Search Results to Christopher Wardell

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One or more keywords matched the following items that are connected to Wardell, Christopher

Item TypeName
Concept Translocation, Genetic
Academic Article Proof of the concept to use a malignant B cell line drug screen strategy for identification and weight of melphalan resistance genes in multiple myeloma.
Academic Article Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations.
Academic Article Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma.
Academic Article Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.
Academic Article A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.
Academic Article Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms.
Academic Article APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma.
Academic Article Identification of a novel t(7;14) translocation in multiple myeloma resulting in overexpression of EGFR.
Academic Article The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma.
Academic Article Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.
Academic Article Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma.
Academic Article An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome.
Academic Article Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns.
Academic Article The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.

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  • Translocation Genetic